Soy Protein-Based Blends, Composites and Nanocomposites by Visakh P. M. Olga Nazarenko & Olga Nazarenko

Author:Visakh P. M.,Olga Nazarenko & Olga Nazarenko
Language: eng
Format: epub
ISBN: 9781119419020
Publisher: John Wiley & Sons, Inc.
Published: 2017-07-14T19:21:00+00:00

5.6 Application of SP in Drug Delivery Systems

Protein-based biomaterials are potential matrices for controlled drug delivery systems. They have been studied extensively because of their biodegradability, biocompatibility, and availability. Their protein networks have the ability to interact with a range of bioactive compounds via their functional groups. These functional groups are useful for reversible binding of bioactive molecules thereby protecting the bioactive moleculesfrom enzymatic attack until they are released at the target site in the body [19, 72]. Hydrolysis of SP by digestive enzymes generates bioactive peptides that may exert a number of physiological effects in vivo on the gastrointestinal, cardiovascular, endocrine, immune and nervous systems [73, 74]. A wide variety of protein-based drug delivery formulations such as films, hydrogels, biocomposites, microparticles, and nanoparticles have been reported (Figure 5.5).

Figure 5.5 Different forms of SP-based drug delivery formulations.

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